GenoPalate has mined through countless scientific articles and invites you to learn the science for yourself directly from some of our sources:

  • Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low. Cardiovasc Diabetol. 2012 Nov 6;11:137. 
  • A Mediterranean diet rich in virgin olive oil may reverse the effects of the -174G/C IL6 gene variant on 3-year body weight change.Mol Nutr Food Res. 2010 May;54 Suppl 1:S75-82. doi: 10.1002/mnfr.200900257.
  • TCF7L2, dietary carbohydrate, and risk of type 2 diabetes in US women. Am J Clin Nutr. 2009 Apr;89(4):1256-62. doi: 10.3945/ajcn.2008.27058. Epub 2009 Feb 11.
  • Dietary fat intake determines the effect of a common polymorphism in the hepatic lipase gene promoter on high-density lipoprotein metabolism: evidence of a strong dose effect in this gene-nutrient interaction in the Framingham Study.Circulation. 2002 Oct 29;106(18):2315-21.
  • Genetic variation in two proteins of the endocannabinoid system and their influence on body mass index and metabolism under low fat diet. Horm Metab Res. 2007 May;39(5):395-7.
  • APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations. Arch Intern Med. 2009 Nov 9;169(20):1897-906. doi: 10.1001/archinternmed.2009.343.
  • CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids. Am J Clin Nutr. 2009 Dec;90(6):1466-75. doi: 10.3945/ajcn.2009.27536. Epub 2009 Oct 21.
  • The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control study. J Transl Med. 2015 Sep 2;13:286. doi: 10.1186/s12967-015-0652-4.
  • Association between NOS3 genetic variants and coronary artery disease in the Han population. Genet Mol Res. 2016 Jun 3;15(2). doi: 10.4238/gmr.15028044.
  • High-Saturated-Fat Diet Increases Circulating Angiotensin-Converting Enzyme, Which Is Enhanced by the rs4343 Polymorphism Defining Persons at Risk of Nutrient-Dependent Increases of Blood Pressure. J Am Heart Assoc. 2017 Jan 17;6(1). pii: e004465. doi: 10.1161/JAHA.116.004465.
  • Beta2-adrenergic receptor genotype affects the renin-angiotensin-aldosterone system response to the Dietary Approaches to Stop Hypertension (DASH) dietary pattern. Am J Clin Nutr. 2010 Aug;92(2):444-9. doi: 10.3945/ajcn.2009.28924. Epub 2010 Jun 2.
  • Dietary n-3 and n-6 polyunsaturated fatty acid intake interacts with FADS1 genetic variation to affect total and HDL-cholesterol concentrations in the Doetinchem Cohort Study. Am J Clin Nutr. 2010 Jul;92(1):258-65. doi: 10.3945/ajcn.2009.29130. Epub 2010 May 19.
  • Polymorphisms in candidate obesity genes and their interaction with dietary intake of n-6 polyunsaturated fatty acids affect obesity risk in a sub-sample of the EPIC-Heidelberg cohort. Eur J Nutr. 2002 Oct;41(5):210-21.
  • Polymorphisms in candidate obesity genes and their interaction with dietary intake of n-6 polyunsaturated fatty acids affect obesity risk in a sub-sample of the EPIC-Heidelberg cohort. Eur J Nutr. 2002 Oct;41(5):210-21.
  • Changes in lifestyle, biological risk factors and total homocysteine in relation to MTHFR C677T genotype: a 5-year follow-up study. Eur J Clin Nutr. 2009 Oct;63(10):1233-40. doi: 10.1038/ejcn.2009.59. Epub 2009 Aug 5.
  • Common cholesteryl ester transfer protein gene variation related to high-density lipoprotein cholesterol is not associated with decreased coronary heart disease risk after a 10-year follow-up in a Mediterranean cohort: Modulation by alcohol consumption. Atherosclerosis. 2010 Aug;211(2):531-8. doi: 10.1016/j.atherosclerosis.2010.03.026. Epub 2010 Mar 27.
  • ADIPOQ polymorphisms, monounsaturated fatty acids, and obesity risk: the GOLDN study. Obesity (Silver Spring). 2009 Mar;17(3):510-7. doi: 10.1038/oby.2008.583. Epub 2008 Dec 18.
  • Attenuated hypercholesterolemic response to a high-cholesterol diet in subjects heterozygous for the apolipoprotein A-IV-2 allele. N Engl J Med. 1994 Sep 15;331(11):706-10.
  • Human cardiovascular disease IBC chip-wide association with weight loss and weight regain in the look AHEAD trial. Hum Hered. 2013;75(2-4):160-74. doi: 10.1159/000353181. Epub 2013 Sep 27.